Treatment of trichomoniasis with a single dose of nimorazole (nitrimidazine).

Nitrimidazine compared with metronidazole in the treatment of vaginal trichomoniasis.

A new substituted nitroimidazole, nitrimidazine (Naxogin), is compared with the established drug, metronidazole (Flagyl), for the treatment of vaginal trichomoniasis in a randomized double-blind trial. Nitrimidazine cured 39 (68%) out of 57 patients and showed no undesirable effects other than nausea in one patient. Metronidazole cured 51 (89%) out of 57 patients and also caused nausea in one p...

Vaginal and oral nitrimidazine in the treatment of vaginal trichomoniasis.

Nitrimidazine in the treatment of trichomoniasis.

women were excluded from the trial. We also planned to treat as many male consorts as possible with the same course of nitrimidazine regardless of whether they had trichomoniasis or not. The women were re-examined as soon as possible after their initial treatment and again after the first and second menstrual periods following therapy. Clinical impressions were ignored and the initial diagnosis...

Treatment of trichomoniasis in females with and without gonorrhoea.

46 women with trichomoniasis and gonorrhea were treated with nimorazole (300 mg twice daily for 7 days) and a trichomonal cure rate of 90-2 per cent. was noted. In addition, 53 of 112 patients with trichomoniasis but without gonorrhoea, were treated with metronidazole (200 mg three times a day for 7 days) and 59 with nimorazole (300 mg twice daily for 7 days) in a randomized trial. The cure rat...

Detection of the antitrichomonal drug nitrimidazine (Naxogin) in urine.

For 10 years vaginal trichomoniasis has been treated by oral chemotherapy. Some cases appear not to respond satisfactorily to the drug used, and it is important to know whether or not the patient is taking the drug, and if so, whether or not it is being absorbed from the alimentary tract. A simple method for detecting these drugs in urine may be of use in such cases. Two antitrichomonal drugs i...